我们正在寻找中国人参与临床研究
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Important Information

If you are interested in applying for this study, please:
  • Read the study description and study information document.
  • Review the Visit Planner dates in your location and confirm that you are available for the stated dates.
  • If you have not yet registered with us, click on the ‘Register’ button at the top of this page and answer the questions.
  • If you have already registered with us, answer the pre-screening questions listed below and submit your interest.

We will then contact you to check your suitability.

Study Information

This study will test an investigational medication, named JADE101, designed for the possible treatment of a type of inflammation that leads to kidney disease.

Immunoglobulin A nephropathy (IgAN) is a chronic kidney disease where the immune system attacks the kidneys and causes inflammation in the kidney’s filtering unit (glomeruli). This chronic inflammation of the kidneys, over time, can lead to a decline in kidney function. Around 30-45% of people diagnosed with IgAN develop kidney failure within 20 to 25 years. The cause of IgAN is unknown, but research suggests that APRIL (A Proliferation Inducing Ligand), a molecule that helps the body make immunoglobulin A (IgA), plays a critical role. In IgAN, an increased APRIL level leads to an increased IgA level triggering kidney damage events.

JADE101 is a monoclonal antibody that is made to block APRIL, and, therefore, reduce the inflammation and protect kidney function.

This is an investigational medicine because it has not been approved by MedSafe or other drug regulatory authorities.

This study (2025 FULL 22946) is being funded by Jade Biosciences, Inc and has been approved by the Northern B Health and Disability Ethics Committee.

Requirements

Healthy Males and Females

  • Aged between 18 – 60 years
  • BMI (Body Mass Index) between 18 – 32 kg/m²
  • Non-smokers/vapers only
  • Not currently taking any regular prescription medications or supplements

What is Involved?

Study Visits: 4-night stay + 12 clinic visits

Reimbursement: Up to $10,000 before tax

Important Documents

Important documents to download and read

Pre-screening Form

Jubilee

Pre screening form for Jubilee

Personal details

Please provide your name, email and phone number so we can contact you. If you have not registered with us before, please REGISTER HERE.

Medical questions

Maximum weight 100kg
Please enter a number from 0 to 159.
Have you had any covid symptoms in the last two weeks or been in isolation?
Have you previously participated in a study with NZCR or any other organisation?
This study requires the use of contraception during the study. If you are in a hetereosexual relationship both partners must agree to use contraception (condoms for males | IUD, birth control or another approved form for females). Are you currently using a form of contraception?
Do you have any history of tuberculosis (TB)?
Do you have any history of allergies, asthma, hay fever, food or drug allergies etc that you are aware of?
Do you have any history of medical conditions relating to:(Required)
Have you taken any prescription, vitamins, supplements, pharmacy medication or over the counter medications in the last 7 days?
If unsure please note down what vaccines you have had in the last month and when or if you plan on receiving any vaccines during the study.
Do you have tattoos or scarring on your abdomen?
Have you donated blood or plasma in the last 4 weeks? Please include last donation date.
Just to inform you, that you come in for screening at risk. There is no payment for the screening visit, and you may not be offered a position on the study if the group fills up. It is not guaranteed that you will get a full position on the study as it depends on your results as well. Are you comfortable with this?
Pre-screening form policy(Required)
I understand that by submitting this form, NZCR will use the information for pre-screening purposes for this study. This information may be recorded on your profile to allow us to improve our process when screening you for a future study. All information provided is confidential. I also understand that by submitting this form, I will be receiving emails, texts or calls about this study. For more information, please refer to the Privacy Policy.