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Important Information

If you are interested in applying for this study, please:
  • Read the study description and study information document.
  • Review the Visit Planner dates in your location and confirm that you are available for the stated dates.
  • If you have not yet registered with us, click on the ‘Register’ button at the top of this page and answer the questions.
  • If you have already registered with us, answer the pre-screening questions listed below and submit your interest.

We will then contact you to check your suitability.

Study Information

This study will test an investigational medication, named NEU-627, designed to treat Multiple Sclerosis (MS). MS is an inflammatory disease of the brain and spinal cord that is the most common cause of neurological disability in young adults. MS causes communication problems between the brain and the rest of the body, leading to various symptoms like fatigue, muscle weakness, and difficulty with coordination and balance.  MS also causes changes in cognitive abilities such as impairments in memory, attention and processing speed. There are around 4,000 people in New Zealand diagnosed with MS. Currently there is no cure for MS, there are only medications with varying efficacy that are used to slow disease progression.

NEU-627 can enter the blood and the brain and works by inhibiting (stopping or blocking) TYK2. TYK2 is known to be important in regulating multiple inflammatory pathways. It is hoped that by regulating inflammation in the brain and spinal cord, it may be an effective treatment for MS.

This is an investigational medicine because it has not been approved by MedSafe or other drug regulatory authorities.

This study (2025 FULL 22600) is being funded by Neuron23 Inc., and has been approved by the Health and Disability Ethics Committee.

Requirements

Healthy Males and Females

  • Aged between 18 – 60 years
  • BMI (Body Mass Index) between 18 – 32 kg/m²
  • Smokers/Vapers allowed
  • Not currently taking any regular prescription medications

What is Involved?

Study Visits: 4-night stay + 1 follow-up phone call

Reimbursement: Up to $2,500 before tax

Important Documents

Important documents to download and read

Pre-screening Form

Illuminate

Pre screening for Illuminate

Personal details

Please provide your name, email and phone number so we can contact you. If you have not registered with us before, please REGISTER HERE.
NZCR Site(Required)
What is your closest site?

Medical questions

Maximum weight 159kg
Please enter a number from 0 to 159.
Have you had any covid symptoms in the last two weeks or been in isolation?
Have you previously participated in a study with NZCR or any other organisation?
This study requires the use of contraception during the study. If you are in a hetereosexual relationship both partners must agree to use contraception (condoms for males | IUD, birth control or another approved form for females). Are you currently using a form of contraception?
Do you have any history of tuberculosis (TB)?
Do you have any history of allergies, asthma, hay fever, food or drug allergies etc that you are aware of?
Do you have any history of medical conditions relating to:(Required)
Have you taken any prescription, vitamins, supplements, pharmacy medication or over the counter medications in the last 7 days?
If unsure please note down what vaccines you have had in the last month and when or if you plan on receiving any vaccines during the study.
Do you have tattoos or scarring that cover more than 25% of your body?
Have you donated blood or plasma in the last 2 months? Please include last donation date.
Just to inform you, that you come in for screening at risk. There is no payment for the screening visit, and you may not be offered a position on the study if the group fills up. It is not guaranteed that you will get a full position on the study as it depends on your results as well. Are you comfortable with this?
Pre-screening form policy(Required)
I understand that by submitting this form, NZCR will use the information for pre-screening purposes for this study. This information may be recorded on your profile to allow us to improve our process when screening you for a future study. All information provided is confidential. I also understand that by submitting this form, I will be receiving emails, texts or calls about this study. For more information, please refer to the Privacy Policy.